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Сorrective influence of Нentabiferon-Сon the immune status of post-weaned piglets and its effectiveness in the prevention of intestinal infections
 
PIIS250026270001834-2-1
DOI10.31857/S250026270001834-2
Publication type Article
Status Published
Authors
G. Vostroilova 
Affiliation: All-Russian research veterinary Institute of pathology, pharmacology and therapy
Address: Russian Federation
A. Shakhov
Affiliation: All-Russian research veterinary Institute of pathology, pharmacology and therapy
Address: Russian Federation
S. Shabunin
Affiliation: All-Russian research veterinary Institute of pathology, pharmacology and therapy
Address: Russian Federation
L. Sashnina
Affiliation: All-Russian research veterinary Institute of pathology, pharmacology and therapy
Address: Russian Federation
P. Parshin
Affiliation: All-Russian research veterinary Institute of pathology, pharmacology and therapy
Address: Russian Federation
L. Cheskidova
Affiliation: All-Russian research veterinary Institute of pathology, pharmacology and therapy
Address: Russian Federation
Yu. Kantorovich
Affiliation: All-Russian research veterinary Institute of pathology, pharmacology and therapy
Address: Russian Federation
Journal nameRossiiskaia selskokhoziaistvennaia nauka
EditionNumber 6
Pages58-61
Abstract

The aim of the research was to study the corrective effect of Gentabiferon-C on the immune status of weaned pigs and its effectiveness in the prevention of intestinal infections. The conducted studies have established a positive effect of the drug on the morphological and immunological parameters of the animal blood, manifested by an increase in comparison with the basic version of the red blood cells content by 10,8%, the relative number of lymphocytes – by 16,5%, the relative and absolute number of T-lymphocytes - by 16,8 and 14,0% and B-cells - by 21,0 and 20,0%, the activity of the complement system - by 23,5%, the lysozyme level - by 66,8%, the phagocytic activity of neutrophils, phagocytic number and index – 15,9; 38,2 and 16,2%, spontaneous and stimulated NBT test – 11,0 and 21,7%, and increased reserve and the index of activation of neutrophils – 13,3 and 17,1%, the number of total immunoglobulin – 9,7%, and high (100%) efficacy in the prevention of intestinal infections caused by the presence in the preparation of antibiotics with a broad spectrum of antimicrobial action and porcine recombinant alpha- and gamma-interferons.

Keywordspost-weaned piglets, intestinal infection, prevention, Hentabiferon-C
Received18.12.2018
Publication date18.12.2018
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1. Pirozhkov M.K., Soboleva G.L. Ehsherikhioz (kolibakterioz) porosyat // Diagnostika i profilaktika osnovnykh infektsionnykh i parazitarnykh boleznej svinej. – Nauchno-proizvodstvennoe ob'edinenie NARVAK. – M., 2005. – S. 29-31.
2. Grechukhin A.N. Vliyanie sindroma MMA u svinomatok na sokhrannost' porosyat-sosunov // Svinovodstvo. – 2010. - №4. – S. 62-63.
3. Pejsak Zigmunt. Zaschita zdorov'ya svinej: Brest: «Poligrafika», 2012. – 644 s.
4. Kolomytsev A.A., Strizhakov A.A., Luk'yanov S.B. Razvitie otechnoj bolezni v assotsiatsii s klassicheskoj chumoj na svinokompleksakh // Aktual'nye problemy boleznej molodnyaka v sovremennykh usloviyakh: Mater. Mezhd. nauch.-prakt. konf. – Voronezh: Voronezhskij gosudarstvennyj universitet, 2002. – S. 15-19.
5. Kuznetsova T. Profilakticheskie premiksy v svinovodstve // Promyshlennoe i plemennoe svinovodstvo. –2006. - №5. – S. 31.
6. Kukushkin S.A. Profilaktika diarejnykh boleznej porosyat v podsosnyj period // Promyshlennoe i plemennoe svinovodstvo. – 2007. - №2. – S. 55-57.
7. Lekhtimyaki Timo. Otechnaya bolezn' porosyat // Svinovodstvo. – 2010. - №4. – S. 36-37.
8. Makarov V.V. O probleme prichinnosti infektsionnykh zabolevanij // Rossijskij veterinarnyj zhurnal. – 2017. - №4. – S. 22- 27.
9. Makarov V.V. Faktornye bolezni // Vestnik Rossel'khozakademii. – 2003. - №5. – S. 11- 14.
10. Shakhov A.G., Brigadirov Yu.N., Sashnina L.Yu., Subbotina S.G. Antagonisticheskaya aktivnost', profilakticheskaya i lechebnaya ehffektivnost' probiotika na osnove Bacillus subtilis pri kolibakterioze (otechnoj bolezni) porosyat // Veterinarnyj vrach. – 2012. - №2. – S. 7-10.
11. Bulgakova V.A. Immunomodulyatory dlya profilaktiki i lecheniya ostrykh respiratornykh infektsij: ehffektivnost' azooksimera bromida // Terapevticheskij arkhiv. – 2014. - №12. – S. 92-97. – doi: 10.17116/terarkh2014861292-97.
12. Karaulov A.V., Kalyuzhin O.V. Immunoterapiya infektsionnykh boleznej: problemy i perspektivy // Terapevticheskij arkhiv. – 2013. – T.85. - №11. – S. 100- 108.
13. Fedorov Yu.N., Klyukina V.I., Romanenko M.N., Bogomolova O.A., Denisenko A.N. Strategiya i printsipy immunokorrektsii i immunomoduliruyuschej terapii // Vestnik Novgorodskogo gosudarstvennogo universiteta. – 2015. - №86. – Ch.1. – S. 84-87.
14. Shabunin S.V., Shakhov A.G., Vostroilova G.A., Sashnina L.Yu., Cheskidova L.V., Kantorovich Yu.A. Vliyanie aminose- letona na immunnyj status belykh krys, vaktsinirovannykh protiv sal'monelleza // Vestnik Rossijskoj sel'skokhozyajstvennoj nauki. – 2017. - №4. – S. 53-56.
15. Viksman M.E., Mayanskij A.N. Sposob otsenki funktsional'noj aktivnosti nejtrofilov cheloveka po reaktsii vosstanovleniya nitrosinego tetrazoliya. – Metodicheskie rekomendatsii. – Kazan', 1979. – 14 s.
16. Pakhmutov I.A., Ul'yanova M.S. Otsenka funktsional'noj aktivnosti nejtrofilov krovi zhivotnykh // Veterinariya. – 1984. - №3. – S. 68-69.

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