A new DNA breaks repair pathway involving PARP3 and base excision repair proteins

 
PIIS086956520003224-9-1
DOI10.31857/S086956520003224-9
Publication type Article
Status Published
Authors
Affiliation: Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the RAS
Address: Russian Federation,
Affiliation: Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the RAS
Address: Russian Federation
Affiliation: Novosibirsk State University
Address: Russian Federation
Affiliation: Institut Gustave Roussy
Address: Russian Federation
Affiliation: Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the RAS
Address: Russian Federation
Journal nameDoklady Akademii nauk
EditionVolume 482 Issue 1
Pages96-100
Abstract

         

Keywords
Received04.11.2018
Publication date04.11.2018
Cite   Download pdf To download PDF you should sign in
Размещенный ниже текст является ознакомительной версией и может не соответствовать печатной

views: 1611

Readers community rating: votes 0

1. Dantuma N.P., van Attikum H., Spatiotemporal regulation of posttranslational modifications in the DNA damage response // EMBO J. 2016. V. 35. J 1. P. 6-23.

2. Kalisch T., Ame J.C., Dantzer F., Schreiber V. New readers and interpretations of poly(ADP-ribosyl)ation // Trends Biochem Sci. 2012. V. 37. J 9. P. 381-904.

3. Caldecott K.W. Protein ADP-ribosylation and the cellular response to DNA strand breaks // DNA Repair. 2014. V. 19. P. 108-113.

4. Boehler C., Gauthier L.R., Mortusewicz O., Biard D.S., Saliou J.M., Bresson A., Sanglier-Cianferani S., Smith S., Schreiber V., Boussin F., Dantzer F. Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression // Proc. Natl. Acad. Sci. U.S.A. 2011. V. 108. P. 2783–2788.

5. Rulten S.L., Fisher A.E., Robert I., Zuma M.C., Rouleau M., Ju L., Poirier G., Reina-San-Martin B., Caldecott K.W. PARP-3 and APLF function together to accelerate nonhomologous end-joining // Mol. Cell. 2011. V. 41. P. 33-45.

6. Rouleau M., McDonald D., Gagne P., Ouellet M.E., Droit A., Hunter J.M., Dutertre S., Prigent C., Hendzel M.J., Poirier G.G. PARP-3 associates with polycomb group bodies and with components of the DNA damage repair machinery // J. Cell Biochem. 2007. V. 100. P. 385-401.

7. Grundy G.J., Polo L.M., Zeng Z., Rulten S.L., Hoch N.C., Paomephan P., Xu Y., Sweet S.M., Thorne A.W., Oliver A.W., Matthews S.J., Pearl L.H., Caldecott K.W. PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2) // Nat. Commun. 2016. V. 7. P. 12404.

8. Talhaoui I., Lebedeva N.A., Zarkovic G., Saint-Pierre C., Kutuzov M.M., Sukhanova M.V., Matkarimov B.T., Gasparutto D., Saparbaev M.K., Lavrik O.I., Ishchenko A.A. Poly(ADP-ribose) polymerases covalently modify strand break termini in DNA fragments in vitro // Nucleic Acids Res. 2016. V. 44. J 19. P. 9279-9295.

9. Zarkovic G., Belousova E.A., Talhaoui I., Saint-Pierre C., Kutuzov M.M., Matkarimov B.T., Biard D., Gasparutto D., Lavrik O.I., Ishchenko A.A. Characterization of DNA ADP-ribosyltransferase activities of PARP2 and PARP3: new insights into DNA ADP-ribosylation // Nucleic Acids Res. 2018. V. 46. J 5. P. 2417-2431.

10. Munnur D., Ahel I. Reversible mono-ADP-ribosylation of DNA breaks // FEBS J. 2017. V. 284. J 23. P. 4002-4016.

11. Belousova E.A., Ishchenko R.A., Lavrik O.I. Dna is a New Target of Parp3 // Sci Rep. 2018. V. 8. J 1. P. 4176.

12. Feng J.A., Crasto C.J., Matsumoto Y. Deoxyribose phosphate excision by the N-terminal domain of the polymerase beta: the mechanism revisited // Biochemistry. 1998. V. 37. J 27. P. 9605-9611.

13. Malfatti M.C., Balachander S., Antoniali G., Koh K.D., Saint-Pierre C., Gasparutto D., Chon H., Crouch R.J., Storici F., Tell G. Abasic and oxidized ribonucleotides embedded in DNA are processed by human APE1 and not by RNase H2 // Nucleic Acids Res. 2017. V. 45. J 19. P. 11193-11212.

14. Belousova E.A., Lavrik O.I. DNA polymerases beta and lambda, and their roles in the DNA replication and repair // Mol Biol (Mosk). 2010. V. 44. J 6. P. 947-965.

15. Liu Y., Beard W.A., Shock D.D., Prasad R., Hou E.W., Wilson SH DNA polymerase beta and flap endonuclease 1 enzymatic specificities sustain DNA synthesis for long patch base excision repair // J Biol Chem. 2005. V. 280. J 5. P. 3665-3674.

Система Orphus

Loading...
Up