Immunological markers of early diagnostics of posttraumatic osteomielitis of the lower jaw

The article presents an assessment of the systemic level of tumor necrosis factor α, interferon γ, interleukin- 4, interleukin-10, matrix metalloproteinase-9 and tissue inhibitor-1 type in patients with posttraumatic osteomyelitis and uncomplicated mandible fractures. The study identifi ed indicators of the system of Pro-and anti-infl ammatory cytokines, indicating their signifi cant role in the immunopathogenesis of post-traumatic osteomyelitis of the mandible. Identifi cation of additional markers for the diagnosis of posttraumatic osteomyelitis of the mandible (TNF, IFN-γ, IL-10), the defi nition of which at the beginning of therapy and the dynamics of its implementation will allow for a more personalized approach to the management of this category of patients

Keywords

trauma, cytokines, osteomyelitis, matrix metalloproteinases

Received

11.01.2019

Publication date

12.01.2019

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GOST	Popova E., Kostyushko A., Dubov V., Milekhina S. Immunological markers of early diagnostics of posttraumatic osteomielitis of the lower jaw // Rossiiskii immunologicheskii zhurnal – 2018. – V. 12. – Issue 3 C. 402-406 [Electronic resource]. URL: http://ras.jes.su/ruimm/s207987840001612-2-1-en (circulation date: 16.01.2025). DOI: 10.31857/S102872210002418-4
MLA	Popova, E., Kostyushko, A., Dubov, V., Milekhina, S. "Immunological markers of early diagnostics of posttraumatic osteomielitis of the lower jaw." Rossiiskii immunologicheskii zhurnal 12.3 (2018):402-406. DOI: 10.31857/S102872210002418-4
APA	Popova E., Kostyushko A., Dubov V., Milekhina S. (2018). Immunological markers of early diagnostics of posttraumatic osteomielitis of the lower jaw. Rossiiskii immunologicheskii zhurnal 12(3), pp.402-406 DOI: 10.31857/S102872210002418-4

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