Immunological markers of early diagnostics of posttraumatic osteomielitis of the lower jaw

 
PIIS102872210002418-4-1
DOI10.31857/S102872210002418-4
Publication type Article
Status Published
Authors
Affiliation: Pacific State Medical University
Affiliation: Pacific State Medical University
Affiliation: Pacific State Medical University
Affiliation: Pacific State Medical University
Journal nameRossiiskii immunologicheskii zhurnal
EditionVolume 12 Issue 3
Pages402-406
Abstract

The article presents an assessment of the systemic level of tumor necrosis factor α, interferon γ, interleukin- 4, interleukin-10, matrix metalloproteinase-9 and tissue inhibitor-1 type in patients with posttraumatic osteomyelitis and uncomplicated mandible fractures. The study identifi ed indicators of the system of Pro-and anti-infl ammatory cytokines, indicating their signifi cant role in the immunopathogenesis of post-traumatic osteomyelitis of the mandible. Identifi cation of additional markers for the diagnosis of posttraumatic osteomyelitis of the mandible (TNF, IFN-γ, IL-10), the defi nition of which at the beginning of therapy and the dynamics of its implementation will allow for a more personalized approach to the management of this category of patients

Keywordstrauma, cytokines, osteomyelitis, matrix metalloproteinases
Received11.01.2019
Publication date12.01.2019
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