Immunobiochemical markers of the gematoentsefalitics barrier and autosensibilization at early forms chronic ischemia of the brain

Davydova, E.; Zurochka, A.; Altman, D.

doi:10.31857/S102872210002392-6

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Rossiiskii immunologicheskii zhurnal

Issue 3

Immunobiochemical markers of the gematoentsefalitics barrier and autosensibilization at early forms chronic ischemia of the brain

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Immunobiochemical markers of the gematoentsefalitics barrier and autosensibilization at early forms chronic ischemia of the brain

PII

S102872210002392-6-1

DOI

10.31857/S102872210002392-6

Publication type

Article

Status

Published

Authors

E. Davydova

Affiliation:
South Ural State Medical University
Chelyabinsk Regional Clinical Hospital

A. Zurochka

Affiliation:
South Ural State University (National Research University)
Federal State Institution of Science Institute of Immunology and Physiology

D. Altman

Affiliation:
South Ural State Medical University
Chelyabinsk Regional Clinical Hospital

Journal name

Rossiiskii immunologicheskii zhurnal

Edition

Volume 12 Issue 3

Pages

261-267

Abstract

The level of neurospecifi c proteins and autoantibodies to the subunit NR2 of the NMDA receptor in veterans with early forms of chronic cerebral ischemia was studied. It was shown that these patients had permeability disturbances of the blood-brain barrier with the growth of autosensibilization processes to brain antigens, which may be one of the mechanisms of progression of chronic cerebral ischemia and a predicted failure of cerebral circulation compensation in patients with progressive course of chronic cerebral ischemia. On the other hand, the defi nition of neurospecifi c proteins in the systemic circulation may be promising for the diagnosis of early stages of chronic cerebral ischemia, when other objective methods of research may be of little informative.

Keywords

early forms of chronic cerebral ischemia, neurospecifi c proteins, autoantibodies to subunit of NR2 NMDA receptor

Received

23.11.2018

Publication date

12.01.2019

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GOST	Davydova E., Zurochka A., Altman D. Immunobiochemical markers of the gematoentsefalitics barrier and autosensibilization at early forms chronic ischemia of the brain // Rossiiskii immunologicheskii zhurnal – 2018. – V. 12. – Issue 3 C. 261-267 [Electronic resource]. URL: http://ras.jes.su/ruimm/s207987840001587-4-1-en (circulation date: 17.01.2025). DOI: 10.31857/S102872210002392-6
MLA	Davydova, E., Zurochka, A., Altman, D. "Immunobiochemical markers of the gematoentsefalitics barrier and autosensibilization at early forms chronic ischemia of the brain." Rossiiskii immunologicheskii zhurnal 12.3 (2018):261-267. DOI: 10.31857/S102872210002392-6
APA	Davydova E., Zurochka A., Altman D. (2018). Immunobiochemical markers of the gematoentsefalitics barrier and autosensibilization at early forms chronic ischemia of the brain. Rossiiskii immunologicheskii zhurnal 12(3), pp.261-267 DOI: 10.31857/S102872210002392-6

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