Elisa detection of cytokine levels to determine the dynamics of the flow inflammatory process

 
PIIS102872210002380-3-1
DOI10.31857/S102872210002380-3
Publication type Article
Status Published
Authors
Affiliation: Orenburg State Medical University
Affiliation: Orenburg State Medical University
Affiliation: Orenburg State Medical University
Affiliation: Orenburg State Medical University
Affiliation: Orenburg State Medical University
Affiliation: Orenburg State Medical University
Affiliation: Orenburg State Medical University
Affiliation: Orenburg State Medical University
Affiliation: The G.N. Gabrichevskii Moscow research institute of epidemiology and microbiology of Rospotrebnadzor of Russia
Journal nameRossiiskii immunologicheskii zhurnal
EditionVolume 12 Issue 3
Pages195-198
Abstract

The work carried out an assessment using ELISA level of serum cytokines and biological fl uids of persons who have undergone purulent-infl ammatory diseases of the urogenital tract. The object of the study was the cytokine profi le of 98 men with gonococcal infection and 40 patients with nonspecifi c urethritis. The study showed that the established values of cytokine levels were used as markers of the volume of urogenital infl ammation, which served as the basis for the development of a method of diagnosis and prediction of the course of the infectious process. The revealed diff erences in the immunocytocin profi le can contribute to the disclosure of the mechanisms of formation of various forms of infection, as well as to determine the methodological and tactical approaches to the treatment and rehabilitation of patients with sexual and reproductive health disorders.

Keywordscytokines, purulent-inflammatory diseases of the urogenital tract, ELISA
Received22.11.2018
Publication date12.01.2019
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1. Gan S. D., Patel K. R. Enzyme immunoassay and enzyme-linked immunosorbent assay. J. Invest Dermatol, 2013, 9, Vol. 133 (9), 12.

2. Belaya O. F., Pak S. G. Ways of improving laboratory diagnosis of infectious diseases. Vestnik RAMN, 2010, 11, 50–53

3. Dolgov V. V., Rakova N. G., Kolupaev V. E., Rytikova N. S. Immunosorbent assay in clinical diagnostic laboratories. Moscow-Tver: Triada, 2007. 320 p

4. Samoylenkov P. V. Immunoassay principles, the main types of ELISA application in diagnostics. Moscow, 2009, RGMU

5. Dinarello C. The biological properties of interleukin-1. Eur. Cytokine Netw., 1994, Vol. 5, 517–526.

6. Kurynin R. M. Achievements national molecular genetics to clinical oncourology. Urologiya segodnya, 2009, no. 4, p. 17 (in Russ.)

7. Gerasimov A. N. Medical statistics. M. MIA. 2007

8. Demyanov A. V., Kotov A. Yu., Simbirtsev A. S. Diagnostic value of cytokine levels research in clinical practice. Cytokines and infl ammation, 2003, Vol. 2, 3, 20–35

9. Zherebyatieva O. O., Setko N. P., Mikhailova E. A., Kirgizova S. B., Konstantinova O. D., Kshnyaseva S. K., Mahalova G. O., Lyashenko I. E. Immunological criteria for forcasting the secondary sterility. Russian Immunological Journal 2015, 9 (18), 2 (1), 378–379. Russian

10. Baggiolini M., Dewald B., Moser B. Human chemokines: an update. Annu. Rev. Immunol., 1997, Vol. 15, 675–705.

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