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Multifunctional analytical system for determining the characteristics of the optical signal of circular dichroism of a biologically active material
 
PIIS086858860002811-4-1
DOI
Publication type Article
Status Published
Authors
F. Vereshchagin 
Affiliation: Institute of Spectroscopy RAS
Address: Russian Federation
S. Skuridin
Affiliation: Institute of Molecular Biology. V.A. Engelhardt RAS
Address: Russian Federation
Yu. Evdokimov
Affiliation: Institute of Molecular Biology. V.A. Engelhardt RAS
Address: Russian Federation
D. Chulkov
Affiliation: RMP "Medtekhnika" UDP RF
Address: Russian Federation
M. Pavlov
Affiliation: Institute of Spectroscopy RAS
Address: Russian Federation
O. Kompanets
Affiliation: Institute of Spectroscopy RAS
Address: Russian Federation
V. Gusev
Affiliation: Institute of Spectroscopy RAS
Address: Russian Federation
Journal nameNauchnoe priborostroenie
EditionVolume 28 Issue 4
Pages39-44
Abstract

The possibility of creating a multifunctional analytical system (biosensor) based on nanoconstructions (NaC) of DNA (biosensing unit) and a portable dichrometer using light-emitting diodes is discussed. Such a system can work in modes of measuring the optical properties of DNA NaC and calibrating the characteristics of the circular dichroism signal of biologically active substance (BAS) interacting with the biosensing unit, as well as in the mode of measuring the diffusion rate of BAS into the biologically active material of the biosensing unit.

Keywordsbiosensor, nanoconstructions DNA, circular dichroism, biologically active substance, diffusion rate
Received02.12.2018
Publication date03.12.2018
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1. Evdokimov Yu.M., Salyanov V.I., Semenov S.V., Skuridin S.G. Zhidkokristallicheskie dispersii i nanokonstruktsii DNK / Pod red. Yu.M. Evdokimova. M.: Radiotekhnika, 2008. 296 s.
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3. Evdokimov Yu.M., Skuridin S.G., Vereschagin F.V., Gusev V.M., Kompanets O.N., Chulkov D.P. Nanokonstruktsii na osnove dvukhtsepochechnykh molekul DNK i ikh opticheskie svojstva // XXV s'ezd po spektroskopii, Troitsk—Moskva, 3–7 oktyabrya 2016 g. Sbornik tezisov. Moskva: MPGU, 2016 (ISBN 978-5-4263-0368-3). S. 219–220.
4. Vereschagin F.V., Gusev V.M., Kompanets O.N., Chulkov D.P., Evdokimov Yu.M., Skuridin S.G. Kompaktnyj dvukhvolnovyj dikhrometr dlya opticheskoj biosensornoj analiticheskoj sistemy meditsinskogo naznacheniya // XXV s'ezd po spektroskopii, Troitsk— Moskva, 3–7 oktyabrya 2016 g. Sbornik tezisov. Mosk- va: MPGU, 2016 (ISBN 978-5-4263-0368-3). S. 284– 285.
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