A compact optical biosensor analytical system for medicine

 
PIIS086858860001096-7-1
DOI10.31857/S086858860001096-7
Publication type Article
Status Published
Authors
Affiliation: Institute of Spectroscopy of the RAS
Address: Russian Federation, Troitsk
Affiliation: Engelhardt Institute of Molecular Biology, RAS
Address: Russian Federation
Affiliation: RMP
Address: Russian Federation
Affiliation: Institute of Spectroscopy of the RAS
Address: Russian Federation
Affiliation: Institute of Spectroscopy of the RAS
Address: Russian Federation
Affiliation: Engelhardt Institute of Molecular Biology, RAS
Address: Russian Federation
Affiliation: Institute of Spectroscopy of the RAS
Address: Russian Federation
Journal nameNauchnoe priborostroenie
EditionVolume 28 Issue 3
Pages54-58
Abstract

An experimental sample of a compact highly sensitive biosensor analytic system for the rapid detection of the presence and concentration of antibiotics (daunomycin and its analogues) used in oncology clinics is created. The optimization of the operation modes of the dichrometer and the elements of the biosensor software was carried out, the biosensor system was calibrated for the example of recording the CD optical signal of containing DAU laboratory solutions.

Keywords biosensor, circular dichroism, DNA based biosensing units, dichrometer, daunomycin
Received08.10.2018
Publication date10.10.2018
Number of characters504
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1. Evdokimov Yu.M., Salyanov V.I., Semenov S.V., Skuridin S.G., Yu.M Evdokimov ed. Zhidko-kristallicheskie dispersii i nanokonstrukcii DNK [Liquid crystal dispersions and nanodesigns of DNA]. Moscow, Radiotekhnika Publ., 2008. 294 p. (In Russ.).

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3. Evdokimov Yu.M., Skuridin S.G., Vereshchagin F.V., Gusev V.M., Kompanets O.N., Chulkov D.P. [Nanode-signs on the basis of two-chained molecules DNA and their optical properties]. XXV s'ezd po spektroskopii: Troick-Moskva, 3–7 oktyabrya 2016 g. Sbornik tezisov [The XXV congress on spectroscopy: Troitsk, Moscow, on October 3–7, 2016. Collection of theses]. Moscow,MPGU, 2016 (ISBN 978-5-4263-0368-3), pp. 219–220.

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5. Vereshchagin F.V., Gusev V.M., Kompanets O.N., Pavlov M.A., Chulkov D.P. [Portable multifunctional dichrometer the new biotouch analytical system of bio-medical appointment on the basis of DNA biosensors]. Biomedicinskaya radioehlektronika [Biomedical Radioe-lectronics], 2013, no. 3, pp. 58–68. (In Russ.).

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