Features of Temperament and Character in Families with Recurrent Depressive and Bipolar Affective Disorders

Occupation: Junior Researcher of the Translational Psychiatry Department
Affiliation: Federal State Budgetary Institution “V.M. Bekhterev National Medical Research Center of Psychiatry and Neurology” of the Ministry of Health of the Russian Federation
Address: Russian Federation, St. Petersburg

A. O. Kibitov

Occupation: Deputy Director for Innovative Scientific Development, Head of the Translational Psychiatry Department
Affiliation:
Federal State Budgetary Institution “V.M. Bekhterev National Medical Research Center of Psychiatry and Neurology” of the Ministry of Health of the Russian Federation
Federal State Budgetary Institution “V.P. Serbsky National Medical Research Center of Ps
Address: Russian Federation, St. Petersburg

G. E. Mazo

Occupation: Head of the Laboratory of Molecular Genetics, Leading Researcher of the Department of Translational Psychiatry
Affiliation: Federal State Budgetary Institution “V.M. Bekhterev National Medical Research Center of Psychiatry and Neurology” of the Ministry of Health of the Russian Federation
Address: Russian Federation, St. Petersburg

Journal name

Psikhologicheskii zhurnal

Edition

Volume 44 Issue 2

Pages

40-49

Abstract

The research is devoted to the study of temperament and character characteristics in families with mood disorders (recurrent depressive disorder (RВВ) and bipolar affective disorder (BD)). Many temperament and character traits tend to aggregate in families and influence the risk of RDD and BD. At the same time, no studies have been conducted in the Russian population with an assessment of temperament and character traits depending on the presence of mood disorders in families. The hypothesis of the study: patients with mood disorders and their relatives have specific features of temperament and character. 36 probands with RDD and BD and 68 of their relatives were examined, as well as 23 probands without mood disorders and 53 of their relatives. A Cloninger's Temperament and Character Inventory (TCI-125) was used to assess personality traits. The results of the study showed that probands with mood disorders, in comparison with their relatives, had significantly higher scores on such TCI-125 dimensions as novelty seeking, harm avoidance, and reward dependence. However, the main contribution to the identified differences was made by relatives without mood disorders. Probands with mood disorders had a higher score on the dimension of harm avoidance compared to healthy probands. In addition, a higher score on the novelty seeking dimension was associated with the absence of relatives with mood disorders when comparing healthy relatives of probands with mood disorders and healthy relatives of probands without mood disorders. It is concluded that there are specific temperament traits in families with mood disorders that can be considered as candidates for the endophenotypes of RDD and BD.

Keywords

temperament, character, depression, bipolar disorder, family study

Publication date

29.03.2023

Number of characters

24068

Cite

GOST	Kasyanov E., Kibitov A., Mazo G. Features of Temperament and Character in Families with Recurrent Depressive and Bipolar Affective Disorders // Psikhologicheskii zhurnal – 2023. – V. 44. – Issue 2 C. 40-49 [Electronic resource]. URL: https://psy.jes.su/S020595920024906-2-1 (circulation date: 17.05.2024). DOI: 10.31857/S020595920024906-2
MLA	Kasyanov, E. D., Kibitov, A. O., Mazo, G. E. "Features of Temperament and Character in Families with Recurrent Depressive and Bipolar Affective Disorders." Psikhologicheskii zhurnal 44.2 (2023):40-49. DOI: 10.31857/S020595920024906-2
APA	Kasyanov E., Kibitov A., Mazo G. (2023). Features of Temperament and Character in Families with Recurrent Depressive and Bipolar Affective Disorders. Psikhologicheskii zhurnal 44(2), pp.40-49 DOI: 10.31857/S020595920024906-2

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