A range of literature sources is devoted to the numerous, steeped by legends and glory events of the century-long history of the Ioffe Physical-Technical Institute (for short, Ioffe Institute), which had a great impact on the development of world science and strengthening of the industrial power and performance capacity of our country. This brief essayis intended to seize the unseizable and to become a guide over the whole history of Ioffe Institute, from foundation to present time, and provide the reader with insight into the grandiosity of what has been done by several generations of its scientists on the background of milestone events in the history of our country.