Correlation Between Expression of KLF5 and ZEB1 Transcription Factor Genes in Pancreatic Cancer

The mRNA content of the transcription factors KLF5 and ZEB1 was studied in pancreatic tumor tissues and in fetal and normal pancreas. Transcription of these factors was not high and similar in normal and fetal pancreatic tissues, whereas it was greatly increased in the pancreatic ductal adenocarcinoma tissues. A significant positive correlation between the KLF5 and ZEB1 transcription levels was observed in the pancreatic tumor tissues.

Keywords

pancreatic ductal adenocarcinoma, KLF5, ZEB1, epithelial–mesenchymal transition, transcription factors.

Received

30.10.2018

Publication date

30.10.2018

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GOST	Zinovieva M., Sverdlov E., Vinogradova T., Kondratieva L., Nikolaev L. Correlation Between Expression of KLF5 and ZEB1 Transcription Factor Genes in Pancreatic Cancer // Doklady Akademii nauk – 2018. – V. 481. – Issue 5 C. 567-569 [Electronic resource]. URL: http://ras.jes.su/dan/s207987840001335-7-1-en (circulation date: 05.05.2024). DOI: 10.31857/S086956520002116-0
MLA	Zinovieva, M., Sverdlov, E., Vinogradova, T., Kondratieva, L., Nikolaev, L. "Correlation Between Expression of KLF5 and ZEB1 Transcription Factor Genes in Pancreatic Cancer." Doklady Akademii nauk 481.5 (2018):567-569. DOI: 10.31857/S086956520002116-0
APA	Zinovieva M., Sverdlov E., Vinogradova T., Kondratieva L., Nikolaev L. (2018). Correlation Between Expression of KLF5 and ZEB1 Transcription Factor Genes in Pancreatic Cancer. Doklady Akademii nauk 481(5), pp.567-569 DOI: 10.31857/S086956520002116-0

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